Halfway by way of his career, Cees Dekker reinvented himself. After several years of hardcore physics, he shifted his focus to ‘nanobiology’ for the turn with the millennium. A term he coined himself, being a make any difference of truth.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
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Non-equilibrium folding of individual DNA molecules recaptured up to 1000 times in a solid state nanopore
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt about het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft achieved veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic buildings to sample spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement with the molecular and cellular degree. Our tasks consist of the following:
Example (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the ceesdekker.net rim on the pore is highlighted in red, and also a 3D rendering from the movement of the DNA rod is shown.
Let's say, rather than applying typical best-down silicon electronics, transistors could be built from The underside up utilizing one organic molecules as being the switching components? This concept, which became The idea of today’s subject of molecular electronics, first emerged from the 1970s.
Resolving the action dimensions in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-making course of action
‘The concept there is such a point for a commencing, a big bang, is currently an interesting signpost to take into account that there was a creator. But extra generally, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: basically, you will discover only atoms and purely natural forces that we can measure.
2006, very first demonstration of molecular sorting inside of a lab on a chip making use of biomotors; discovery of nanobubbles in stable-point out nanopores; and initial estimate of electrokinetic Strength conversion inside of a nanofluidic channel
Visualization of unstained DNA nanostructures with Sophisticated in-emphasis transmission electron microscopy approaches
Stable-point out nanopores have tested to generally be a surprisingly versatile probe for single-molecule analysis of DNA. I'll explain several of our new results – exclusively DNA knots – and also our initiatives to grow the capabilities of sound-state nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.